Non-Invasive Vagus Nerve Stimulation Shows Potential in Proof-of-Concept Study for Rheumatoid Arthritis Relief

by | Jan 8, 2024 | News

The vagus nerve, also known as the tenth cranial nerve, is a key component of the autonomic nervous system. It is the longest of the cranial nerves and plays a vital role in regulating various bodily functions, including heart rate, digestion, respiratory rate, and other involuntary processes. The vagus nerve is responsible for the parasympathetic nervous system, often referred to as the “rest and digest” system, as it promotes relaxation and helps the body recover after stress. Stimulation of the vagus nerve has been explored for its potential therapeutic effects on various medical conditions, including rheumatoid arthritis and other inflammatory disorders.

Vagus nerve stimulation has emerged as a promising avenue for exploring alternative treatments in rheumatoid arthritis (RA) management. A recent study employing implanted devices has shown positive outcomes in mitigating RA severity, indicating the potential therapeutic impact of stimulating the vagus nerve. The device used was well-tolerated by patients, and there were notable reductions in DAS28-CRP, indicating potential efficacy in treating rheumatoid arthritis. DAS28-CRP is an objective measure of disease activity in rheumatoid arthritis. 

The exploration of such innovative interventions holds the potential to reshape the landscape of RA care, providing novel avenues for patients seeking effective and well-tolerated alternatives.

It’s important to note that this was an uncontrolled, open-label study, and the results should be considered within this context. To establish the validity of this non-invasive approach as a viable treatment for rheumatoid arthritis, further investigation through larger, controlled studies is imperative.

Source:

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30425-2/fulltext?fbclid=IwAR08xiwL53vJsZ2h0dQytjuHmFSb-9aj5qwtDe0wThxZcZw7V4an5FndR3A

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