Can GLP-1 medications like Wegovy, Zepbound, Mounjaro, Ozempic, semaglutide, and tirzepatide help reduce arthritis symptoms, rheumatoid arthritis inflammation, and autoimmune disease activity? Emerging research suggests these medications may offer benefits beyond weight loss, potentially impacting the inflammatory pathways involved in chronic autoimmune conditions. In this video, I break down the latest studies and what they could mean for people living with arthritis and autoimmune disease.

As a rheumatologist, I explain how semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) may influence inflammation, immune system activity, joint pain, and overall autoimmune health. I also discuss the newest medication in this class, retatrutide, along with potential benefits, risks, and side effects.